Why the study?
Does neuraminidase injection reduce the number of metastases in mice inoculated with TA3 ascites tumor cells?
Population
Mice inoculated with TA3 ascites tumor cells
Design
Preclinical
Authors
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Hypothesis-generating for antimetastatic neuraminidase strategies; leaves open translation to other models or humans.
Does neuraminidase injection reduce the number of metastases in mice inoculated with TA3 ascites tumor cells?
Neuraminidase injection prior to tumor cell inoculation reduces metastasis formation in mice, potentially by altering cell stickiness.
Gasic et al. (1968) studied this question.
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