September 1, 1974Clinical Genetics
Lp(a) lipoprotein and pre‐β1‐lipoprotein in patients with coronary heart disease
Why the study?
Is pre-β1-lipoprotein closely related to Lp(a) lipoprotein and associated with coronary heart disease?
Population
Finnish patients with coronary heart disease (CHD)
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May support Lp(a) measurement for CHD risk assessment; leaves open prospective validation before clinical adoption.
Structured PICO
Is pre-β1-lipoprotein closely related to Lp(a) lipoprotein and associated with coronary heart disease?
P
Population
Finnish patients with coronary heart disease (CHD)
O
Outcome
Relationship between pre-β1-lipoprotein and Lp(a) lipoprotein, and between Lp(a) lipoprotein and CHDsurrogate
Pre-β1-lipoprotein is closely related or identical to Lp(a) lipoprotein, suggesting its potential utility as a biomarker for identifying individuals at high risk for developing coronary heart disease.
Cite This Study
Berg et al. (1974) studied this question.