February 6, 2008Journal of NeuroscienceOpen Access

Beyond Feeling: Chronic Pain Hurts the Brain, Disrupting the Default-Mode Network Dynamics

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Population

Chronic back pain (CBP) patients and healthy controls

Design

Case-control

Authors

MBMarwan N. BalikiNorthwestern University PGPaul GehaUniversity of Rochester Medical Center AAA. Vania ApkarianPurchase College

Discussion

Member takes

Implication

May underlie cognitive issues in chronic back pain; hypothesis-generating and should not yet change practice.

Structured PICO

Population

Chronic back pain (CBP) patients and healthy controls

Comparator

Healthy controls

Outcome

Deactivation in default mode network (DMN) regions during a visual attention task measured by fMRIsurrogate

Chronic back pain is associated with disrupted default mode network dynamics, which may underlie the cognitive and behavioral impairments seen in these patients.

Cite This Study

Baliki et al. (2008) studied this question.

synapsesocial.com/papers/69ff714464548b97a42d68f0 https://doi.org/10.1523/jneurosci.4123-07.2008

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