Why the study?
Because the liver receives about one-quarter of total cardiac output and is sensitive to hemodynamic changes, the authors aimed to investigate AST/ALT ratio changes in acute myocardial infarction patients without liver disease history in the Chinese Han population.
Does the AST/ALT ratio predict total coronary occlusion in patients with acute myocardial infarction?
Does the AST/ALT ratio predict total coronary occlusion in patients with acute myocardial infarction?
Answers are grounded in this paper and cite their sources.
An AST/ALT ratio ≥ 2.0 upon admission is strongly associated with total coronary occlusion in patients with acute myocardial infarction.
INTRODUCTION: Fernando De Ritis described the significance of the transaminase (AST/ALT) ratio in 1957, and since then it has been commonly used to screen liver diseases. The liver is sensitive to hemodynamic changes because it receives approximately one-quarter of total cardiac output. We aimed to investigate the AST/ALT ratio changes in patients with acute myocardial infarction without any history of liver diseases in the Chinese Han population. MATERIAL AND METHODS: We analyzed a total of 120 patients with acute myocardial infarction admitted to the cardiology department of Zhongnan Hospital of Wuhan University between January 2019 and June 2019. AST/ALT ratio of the first blood test was calculated for all patients. CONCLUSIONS: AST/ALT ≥ 2.0 has a strong association with total coronary occlusion. We might rely on this test to predict coronary occlusion without age difference.
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Djakpo et al. (2020) studied this question.
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