Answers are grounded in this paper and cite their sources.
) reprograms Epi-iBMECs into authentic endothelial cells that are congruent with bona fide endothelium at both transcriptomic as well as some functional levels. This approach could eventually be used to develop a robust human BBB model in vitro that resembles the human brain EC in vivo for functional studies and drug discovery.
No takes yet. Share an insight, caveat, or question.
Lu et al. (2021) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: