Population
Muscle cells (including cardiac and skeletal muscle) and dystrophic mdx muscles
Design
Review
Authors
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Impaired MGF response may limit repair in dystrophy; leaves open targeted validation in human models before clinical consideration.
The discovery of locally produced mechano growth factor (MGF) provides a link between mechanical stimulus and gene expression for muscle repair, a mechanism found to be defective in muscular dystrophies.
Geoffrey Goldspink (1999) studied this question.
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