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November 9, 2017PLoS ONEOpen Access

Does preoperative mechanical prophylaxis have additional effectiveness in preventing postoperative venous thromboembolism in elderly patients with hip fracture?—Retrospective case-control study

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Why the study?

Does preoperative mechanical thromboprophylaxis reduce postoperative venous thromboembolism in elderly patients aged 70 years or older undergoing hip fracture surgery?

Population

539 consecutive patients aged 70 years or older undergoing hip fracture surgery (HFS)

Comparison

Preoperative mechanical thromboprophylaxis using… vs No preoperative mechanical thromboprophylaxis…

Design

Case-control

Follow-up

within one month of surgery

Authors

JNJi‐Hoon NamSK Group (South Korea)DKDaehwan KimUniversity of UlsanJYJe‐Hyun YooHallym University

Discussion

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Overview

Preoperative mechanical thromboprophylaxis was associated with lower symptomatic DVT; leaves open effect on overall VTE and requires randomized confirmation.

Structured PICO

Does preoperative mechanical thromboprophylaxis reduce postoperative venous thromboembolism in elderly patients aged 70 years or older undergoing hip fracture surgery?

P
Population
539 consecutive patients aged 70 years or older undergoing hip fracture surgery (HFS)
I
Intervention
Preoperative mechanical thromboprophylaxis using an intermittent pneumatic compression device and graduated compression stockings from the time of admission until surgery, in addition to combined postoperative mechanical and chemical thromboprophylaxis
C
Comparator
No preoperative mechanical thromboprophylaxis, but received combined postoperative mechanical and chemical thromboprophylaxis following HFS in accordance with the same protocol
O
Outcome
Incidence of symptomatic VTE (DVT and PE) confirmed based on clinical symptoms and 3-dimensional CT angiography within one month of surgeryhard clinical

Preoperative mechanical thromboprophylaxis significantly reduces the risk of symptomatic DVT in elderly patients undergoing hip fracture surgery without increasing perioperative bleeding risk.

Cite This Study

Nam et al. (2017) studied this question.

synapsesocial.com/papers/69ff9bca10d6befb25774e7ehttps://doi.org/10.1371/journal.pone.0187337
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence of venous thromboembolism and hemorrhage related safety studies of preoperative anticoagulation therapy in hip fracture patients undergoing surgical treatment: a case–control study2016 · 22 citations
  2. 2Risk Factors for Clinically Relevant Pulmonary Embolism and Deep Venous Thrombosis in Patients Undergoing Primary Hip or Knee Arthroplasty2003 · 239 citations
  3. 3Risk Factors for Venous Thromboembolism in Patients Undergoing Total Hip Replacement and Receiving Routine Thromboprophylaxis2010 · 131 citations
  4. 4Preoperative versus postoperative initiation of thromboprophylaxis following major orthopedic surgery: safety and efficacy of postoperative administration supported by recent trials of new oral anticoagulants2011 · 24 citations
  5. 5Excess Length of Stay, Charges, and Mortality Attributable to Medical Injuries During Hospitalization2003 · 1,044 citations