Why the study?
Angina and nonobstructive coronary arteries is increasingly recognized, but the impact of age and sex on coronary microvascular function in this population has received limited study.
Do age and sex impact coronary flow reserve and microvascular function in patients with angina and nonobstructive coronary arteries?
Population
206 consecutive patients with angina and nonobstructive coronary arteries
Comparison
Age and sex associations and age-related trends in men vs women
Design
Cross-sectional observational study
Authors
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Does not support practice changes by age or sex; hypothesis-generating for sex-specific microvascular research.
Do age and sex impact coronary flow reserve and microvascular function in patients with angina and nonobstructive coronary arteries?
Age-related impairment in coronary microvascular function is more pronounced in women than men among patients with angina and nonobstructive coronary arteries.
Kostantinis et al. (2025) studied this question.