Diagnosis and outcomes of cachexia in Asia: Working Consensus Report from the Asian Working Group for Cachexia

Hidenori Arai; Keisuke Maeda; Hidetaka Wakabayashi; Tateaki Naito; Masaaki Konishi; Prasert Assantachai; Wai Tung Auyeung; Chalobol Chalermsri; Wei Chen; Justin Chew; Ming‐Yueh Chou; Chih‐Cheng Hsu; Allyn Hum; In Gyu Hwang; Toshimi Kaido; Lin Kang; Shahrul Bahyah Kamaruzzaman; Miji Kim; Jenny Shun Wah Lee; Wei‐Ju Lee; Chih‐Kuang Liang; Wee Shiong Lim; Jae‐Young Lim; Yen Peng Lim; Raymond See‐Kit Lo; T. Ong; Wen‐Harn Pan; Li‐Ning Peng; Pornpoj Pramyothin; Nurul Huda Razalli; Masakazu Saitoh; Suzana Shahar; Hanping Shi; Heng‐Hsin Tung; Yasuhito Uezono; Stephan von Haehling; Chang Won Won; Jean Woo; Liang‐Kung Chen

doi:10.1002/jcsm.13323

Key Points

Establish a tailored consensus definition, diagnostic criteria, and critical clinical outcome measures for cachexia in Asian populations.
Convened an expert panel from the Asian Working Group for Cachexia (AWGC) to formulate regional diagnostic criteria and clinical recommendations.
Evaluated diagnostic thresholds for low body mass index alongside functional and quality-of-life assessment instruments, including EQ-5D, the Functional Assessment of Anorexia/Cachexia Therapy, Clinical Frailty Scale, and Barthel Index.
Defined user-friendly, Asian-specific diagnostic criteria for cachexia that incorporate appropriate body mass index cutoffs.
Identified mortality, functional status (evaluated via Clinical Frailty Scale or Barthel Index), and patient-reported quality of life as critical clinical outcomes.

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Implication

Consensus report defines tailored diagnostic criteria for cachexia in Asian populations, indicating a path toward standardized multidisciplinary care.

Abstract

for low body mass index in diagnosing cachexia. Critical clinical outcomes were determined to be mortality, quality of life as assessed by tools such as EQ-5D or the Functional Assessment of Anorexia/Cachexia Therapy, and functional status as measured by the Clinical Frailty Scale or Barthel Index, with significant emphasis on patient-reported outcomes. The AWGC consensus offers a comprehensive definition and user-friendly diagnostic criteria for cachexia, tailored specifically for Asian populations. This consensus is set to stimulate future research and enhance the multidisciplinary approach to managing cachexia. With plans to develop further guidelines for the optimal treatment, prevention, and care of cachexia in Asians, the AWGC criteria are expected to drive research across chronic co-morbidities and cancer in Asia, leading to future refinement of diagnostic criteria.

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Cite This Study

Arai et al. (2023) studied this question.

synapsesocial.com/papers/69ffc3a4831589f3542da6a0 https://doi.org/10.1002/jcsm.13323

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Diagnosis and outcomes of cachexia in Asia: Working Consensus Report from the Asian Working Group for Cachexia

Key Points

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Implication

Abstract

Discussion

Cite This Study

Diagnosis and outcomes of cachexia in Asia: Working Consensus Report from the Asian Working Group for Cachexia

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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