Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1How Do CD4+ T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?2014 · 205 citations
2. 2Aging and Cytomegalovirus Infection Differentially and Jointly Affect Distinct Circulating T Cell Subsets in Humans2014 · 361 citations
3. 3Physical Independence and Mortality at the Extreme Limit of Life Span: Supercentenarians Study in Japan2013 · 78 citations
4. 4Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer2017 · 1,079 citations
5. 5Cytotoxic CD4⁺ T cells in viral hepatitis2006 · 154 citations