Age-related changes in the biomechanics of left ventricular twist measured by speckle tracking echocardiography
Why the study?
Does advancing age alter left ventricular twist biomechanics measured by speckle tracking echocardiography in healthy individuals?
Population
61 healthy volunteers divided into three age groups, including 31 men.
Comparison
Advancing age (observational) vs Younger age groups
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Supports age-specific LV twist norms on STE; extends cross-sectional data but leaves open prognostic value.
Structured PICO
Does advancing age alter left ventricular twist biomechanics measured by speckle tracking echocardiography in healthy individuals?
P
Population
61 healthy volunteers divided into three age groups (16-35 yr, n=25; 36-55 yr, n=23; 56-75 yr, n=13), including 31 men.
I
Intervention
Advancing age (observational)
C
Comparator
Younger age groups
O
Outcome
Left ventricular rotation parameters including Rot(early), Rot(max), Twist(max), time to these parameters, and rotational deformation delay measured by speckle tracking echocardiographysurrogate
Advancing age is associated with increased maximal left ventricular twist due to increased apical rotation and decreased rotational deformation delay, which may help preserve ejection fraction in the elderly.
Cite This Study
Dalen et al. (2008) studied this question.