Why the study?
Do specific cardiovascular risk factors differentially associate with raised atherosclerotic lesions in coronary versus cerebral arteries in middle-aged men?
Do specific cardiovascular risk factors differentially associate with raised atherosclerotic lesions in coronary versus cerebral arteries in middle-aged men?
Different vascular beds may have distinct primary drivers of atherosclerosis, with lipid profiles being most significant for coronary arteries and blood pressure for cerebral arteries.
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May indicate bed-specific atherosclerosis drivers; hypothesis-generating and should not yet change practice.
Holme et al. (1981) studied this question.