Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 1, 2021NanomaterialsOpen Access

Fundamentals to Apply Magnetic Nanoparticles for Hyperthermia Therapy

View Full Paper
Ask AI
Bookmark
Share

Authors

HFHira FatimaTCTawatchai CharinpanitkulKKKyo‐Seon Kim

Discussion

Loading...

Member takes

Overview

Review demonstrates how nanoparticle synthesis, coating, and field parameters govern tumor heating efficiency, highlighting strategies to optimize magnetic hyperthermia therapy.

Key Points

  • To review the physical, chemical, and biological principles underlying magnetic nanoparticle heating in cancer hyperthermia, bridging material synthesis with clinical therapeutic applications.
  • Synthesized evidence on magnetic nanoparticle characteristics, including core materials, surface coatings, geometries, and surface charges.
  • Evaluated the impact of alternating magnetic field parameters (amplitude and frequency), heat loss mechanisms, and in vivo protein corona formation on thermal dose delivery.
  • Nanoparticle heating efficiency depends directly on the product of the applied alternating magnetic field amplitude and its frequency.
  • Variations in nanoparticle shape, coating materials, surface charge, and physiological protein corona formation significantly alter heat dissipation and therapeutic dose precision.

Cite This Study

Fatima et al. (2021) studied this question.

synapsesocial.com/papers/69ffd05d6be84a7ac885569fhttps://doi.org/10.3390/nano11051203
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Magnetic Interaction of Multifunctional Core–Shell Nanoparticles for Highly Effective Theranostics2018 · 66 citations
  2. 2Protein-passivated Fe3O4 nanoparticles: low toxicity and rapid heating for thermal therapy2008 · 190 citations
  3. 3PSMA-targeting Iron Oxide Magnetic Nanoparticles Enhance MRI of Preclinical Prostate Cancer2014 · 105 citations
  4. 4Magnetic Nanoparticles: Synthesis, Protection, Functionalization, and Application2007 · 6,776 citations
  5. 5Theranostic Magnetic Nanoparticles2011 · 725 citations