Population
Patients with rheumatoid arthritis (RA)
Design
Review
Authors
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Hypothesis-generating for viral-IFN-alpha-survivin axis in RA; does not alter practice and requires prospective validation.
This review highlights the potential mechanistic link between viral infections, IFN-alpha production, and survivin expression in driving joint destruction in rheumatoid arthritis.
Bokarewa et al. (2007) studied this question.
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