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June 23, 2016The Open Orthopaedics JournalOpen Access

Preoperative Determinants of Patient-reported Pain and Physical Function Levels Following Total Knee Arthroplasty: A Systematic Review

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Why the study?

What are the preoperative determinants of patient-reported pain and physical function levels following total knee arthroplasty?

Population

Participants undergoing primary unilateral total knee arthroplasty with a follow-up from 6 months to 2 years

Design

Systematic_review

Follow-up

6 months to 2 years

Authors

ELEugen LunguCentre Hospitalier de l’Université de MontréalPVPascal‐André VendittoliArthritis SocietyFDFrançois DesmeulesUniversité de Sherbrooke

Discussion

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Implication

Supports preoperative risk stratification and counseling; confirms key predictors and extends need for targeted intervention trials.

Structured PICO

What are the preoperative determinants of patient-reported pain and physical function levels following total knee arthroplasty?

P
Population
Participants undergoing primary unilateral total knee arthroplasty (TKA) with a follow-up from 6 months to 2 years (33 prognostic explanatory studies included)
I
Intervention
Total knee arthroplasty (TKA)
O
Outcome
Early and medium term patient-reported pain and disability following TKA measured by validated disease-specific patient-reported outcome measurespatient reported

Preoperative factors such as socioeconomic deprivation, psychological distress, worse baseline pain/function, and comorbidities are significant determinants of worse short- to medium-term pain and functional outcomes after total knee arthroplasty.

Limitations

  • Heterogeneity of study methodologies and results preventing conclusions regarding the strength of associations

Cite This Study

Lungu et al. (2016) studied this question.

synapsesocial.com/papers/69ffe1a864548b97a42d75a7https://doi.org/10.2174/1874325001610010213
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Also Consider

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  1. 1Evaluation of the Quality of Prognosis Studies in Systematic Reviews2006 · 1,467 citations
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  4. 4Prevalence of Clinically Significant Improvement Following Total Knee Replacement2011 · 47 citations
  5. 5Predictors of outcomes of total knee replacement surgery2012 · 374 citations