Trends in Uptake and Adherence to Oral Anticoagulation for Patients With Incident Atrial Fibrillation at High Stroke Risk Across Health Care Settings

Figure 1. Uptake of OAC at 90 days over study period in patients at high stroke risk stratified by locale. OAC indicates oral anticoagulant.

Figure 2. Oral anticoagulation adherence stratified by locale. DOAC adherence by proportion of days covered in patients at high stroke risk stratified by locale (left). Warfarin control by time‐in‐therapeutic range ≥65% in patients at high stroke risk stratified by locale (right). DOAC indicates direct oral anticoagulant.

Figure 3. Predictors of OAC adherence. Odds ratios (ORs) and 95% CIs for factors affecting high DOAC adherence and high warfarin adherence. ORs and 95% CIs for factors affecting high DOAC adherence and high warfarin adherence. Predictors of DOAC and warfarin adherence with references are given on the left and right, respectively. DOAC adherence was assessed with proportion of days covered, while warfarin adherence was assessed with TTR. DOAC indicates direct oral anticoagulant; ED, emergency department; OAC, oral anticoagulant; and TTR, time in therapeutic range.

Figure 4. All‐cause mortality by 3‐year adherence category. Kaplan–Meier curves of all‐cause mortality by adherence category is shown for DOACs and warfarin on the left and right, respectively. DOAC indicates direct oral anticoagulants; PDC, proportion of days covered; and TTR, time in therapeutic range.