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This report aims to document a rare case of metastatic canine cutaneous clear cell adnexal carcinoma (CCCCAC) in an 11-year-old dog.

Metastatic canine cutaneous clear cell adnexal carcinoma: case report

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Case report describes metastatic canine cutaneous clear cell adnexal carcinoma, indicating aggressive behavior in dogs.

This report aims to document a rare case of metastatic canine cutaneous clear cell adnexal carcinoma (CCCCAC) in an 11-year-old dog.
Fine-needle aspiration cytology was performed to support the diagnosis.
Histopathological analysis was conducted, revealing a multilobulated neoplasm with aggressive features.
Immunohistochemical staining characterized the neoplastic cells.
The dog displayed marked metastasis to lymph nodes, lungs, and pancreas despite supportive care.
Histopathology confirmed a malignant epithelial neoplasm with high mitotic activity and significant lymphovascular invasion.
This case represents the first reported instance of metastatic CCCCAC in Brazil.

Schiavi et al. (2026) studied this question.

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