Study on the preparation of postbiotic elements by fermentation of wheat by-products and their role in improving constipation

Key Points

• The study aims to explore how postbiotics created from fermented wheat by-products can relieve constipation.
• Co-fermentation of wheat by-products with L. paracasei was conducted.
• Assessment of the resulting postbiotic-rich ingredient's effects on gut microbiota and signaling pathways was performed.
• The postbiotic-rich ingredient significantly improved gut microbiota composition.
• Alleviation of constipation was observed through enhanced SCFA-5-HT signaling.