Promising Synthetic Antioxidants of Dimethyltin(IV) Formulations Derived From 4‐Acylated Edaravone: Design, DFT Assisted Optimized Molecular Structure and Mechanistic Insights into SET Versus HAT Pathways for Antioxidant Activity

Key Points

• This research aims to explore the antioxidant activity of dimethyltin(IV) complexes derived from 4-acylated edaravone.
• Calculated molecular structures using DFT-B3LYP functional in Spartan 20 software.
• Tested antioxidant activity through DPPH assay.
• Investigated mechanistic pathways involving SET and HAT processes.
• Dimethyltin(IV) complexes show significant antioxidant activity based on DPPH assay results.
• Mechanistic insights reveal insights into SET versus HAT pathways for antioxidant action.