0457 Doxepin and Mirtazapine Use in Children and Adolescents with Symptoms of Insomnia – A Single-Center Retrospective Review
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Key Points
The study aims to evaluate the efficacy, tolerability, and safety of doxepin and mirtazapine in treating pediatric insomnia after previous treatments failed.
Retrospective single-center chart review of patients under 18 years of age
Included children who failed behavioral interventions and melatonin
Patients treated with doxepin (2-10mg) and/or mirtazapine (1.875-15mg), with follow-up assessments using a 4-point Likert scale.
In the doxepin group, 167 patients (91.26%) showed improvement in insomnia symptoms.
In the mirtazapine group, 16 patients (66.67%) experienced improvement in symptoms.
In the doxepin-mirtazapine group, 13 patients (68.42%) reported symptom improvement.
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Implication
Retrospective review assesses doxepin and mirtazapine efficacy for insomnia in children, suggesting effective treatment options.