What question did this study set out to answer?

This study aims to assess daytime symptoms, particularly sleepiness and fatigue, alongside psychological distress in patients with COMISA compared to those with OSA.

May 10, 2026SLEEP

1026 Daytime Symptom Burden and Psychological Distress in Greek Patients with Obstructive Sleep Apnea and COMISA: Findings from a Clinical Cohort

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This study aims to assess daytime symptoms, particularly sleepiness and fatigue, alongside psychological distress in patients with COMISA compared to those with OSA.
Data collected from three Sleep Medicine Clinics in Greece.
Participants underwent polysomnography or home sleep testing and completed validated questionnaires: ESS, FSS, AIS, HADS-A/HADS-D.
Statistical analyses compared the OSA and COMISA groups.
407 patients with COMISA exhibited significantly higher excessive daytime sleepiness (EDS) rates (40.5% vs. 17.9%, p<0.001) compared to OSA group.
COMISA patients had more severe fatigue (63.6% vs. 25.7%, p<0.001) and increased anxiety (45% vs. 12.4%, p<0.001) and depressive symptoms (48.6% vs. 18.3%, p<0.001) than those with OSA.

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Implication

Randomized trial evaluates daytime symptoms and psychological distress in Greek patients with COMISA, suggesting complex clinical management is necessary.

Cite This Study

Athanasiou et al. (2026) studied this question.

synapsesocial.com/papers/6a0020cec8f74e3340f9ba4d https://doi.org/10.1093/sleep/zsag091.1025

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Implication

Randomized trial evaluates daytime symptoms and psychological distress in Greek patients with COMISA, suggesting complex clinical management is necessary.

1026 Daytime Symptom Burden and Psychological Distress in Greek Patients with Obstructive Sleep Apnea and COMISA: Findings from a Clinical Cohort

Key Points

Discussion

Implication

Cite This Study

1026 Daytime Symptom Burden and Psychological Distress in Greek Patients with Obstructive Sleep Apnea and COMISA: Findings from a Clinical Cohort

Key Points

Discussion

Implication

Cite This Study

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