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May 10, 2026Sensors & DiagnosticsOpen Access

Establishment of a peptide-based electrochemical immunosensor for detecting antibodies against the GP5 protein from the porcine reproductive and respiratory syndrome virus

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Randomized trial demonstrates effective detection of PRRSV antibodies in pig serum, indicating a novel diagnostic tool.

To develop a peptide-based electrochemical immunosensor for detecting antibodies against PRRSV in pig serum.
Utilized electrochemical impedance spectroscopy (EIS) to measure changes in electron transfer resistance.
Functionalized a gold electrode with synthetic viral peptide for specific antibody binding.
Tested the sensor with pig serum samples to monitor antibody presence.
Successfully detected anti-PRRSV antibodies, indicating high sensitivity of the sensor.
Demonstrated significant changes in electron transfer resistance upon antigen-antibody binding.
Validation shows promising application potential for disease monitoring in livestock.

Franco-Correa et al. (2026) studied this question.

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