What question did this study set out to answer?

To develop a novel near-infrared AIEgen from rofecoxib for monitoring lipid droplet metabolism in real-time.

May 10, 2026New Journal of Chemistry0 citations

Facile transformation of rofecoxib into a novel near-infrared AIEgen for real-time dynamic monitoring of lipid droplets metabolism

TDTao DaiTongji University RLRenfu LiChinese Academy of Sciences TWTong WuTianjin University of Traditional Chinese Medicine

Key Points

To develop a novel near-infrared AIEgen from rofecoxib for monitoring lipid droplet metabolism in real-time.
Transforming rofecoxib into a near-infrared AIEgen
Monitoring lipid droplets formation and degradation
Employing real-time visual techniques to observe dynamic movement
Successfully created a near-infrared AIEgen from rofecoxib
Enabled real-time monitoring of lipid droplets with enhanced clarity
Provided new insights into lipid metabolism dynamics

Abstract

Lipid-related diseases that surpass other diseases cause a significant number ofglobal deaths each year. Visual monitoring the formation, dynamic movement and degradation of lipid droplets (LDs) can enhance our understanding...

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