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May 10, 2026Biofabrication0 citationsOpen Access

A 3D-printed osteochondral scaffold with a dual biomimetic design of spatially organized lotus-radial microchannels and bioinspired nano-mineral precursors for efficient osteochondral regeneration

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QJQi JiangYWYicong WuZDZiyu Ding

Key Points

  • The research aims to assess the effectiveness of a dual biomimetic scaffold design for osteochondral regeneration.
  • Evaluations of nCaP/GelMA scaffold performance compared to control groups.
  • Measurement of tissue integration and mechanical performance.
  • Assessment of restoration of hierarchical architecture.
  • The nCaP/GelMA scaffold showed improved tissue integration compared to control groups.
  • Enhanced mechanical performance was observed with the dual biomimetic design.
  • Restoration of hierarchical architecture was achieved effectively.

Abstract

evaluations demonstrated that the nCaP/GelMA scaffold achieved improved tissue integration, restoration of hierarchical architecture, and enhanced mechanical performance compared with control groups. These findings underscore the potential of dual biomimetic scaffold design as an effective strategy for osteochondral regeneration.

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Cite This Study

Jiang et al. (2026) studied this question.

synapsesocial.com/papers/6a002162c8f74e3340f9c312https://doi.org/10.1088/1758-5090/ae61f6
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