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May 10, 2026Journal of Clinical MedicineOpen Access

Predicting Postoperative Complications After Cholecystectomy for Acute Cholecystitis: Comparative Performance of Disease-Specific and General Prognostic Scores

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Authors

MMM MarcianòUniversity of PalermoGSGiuseppe SalamoneUniversity of PalermoGGGiovanni GuercioUniversity of Palermo

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Implication

Retrospective study compares risk scores for predicting complications and hospital stay in acute cholecystitis patients, suggesting improved stratification.

Key Points

  • This study aims to compare the effectiveness of different prognostic scores in predicting postoperative complications and prolonged hospital stay after cholecystectomy for acute cholecystitis.
  • Single-center retrospective study with 211 patients undergoing cholecystectomy for acute cholecystitis
  • Compared five prognostic scores: Chole-Risk, Chole-Risk mod, POSSUM PS, APACHE II, CCI
  • Discriminative performance evaluated using AUC and pairwise comparisons with the DeLong test
  • Postoperative complications occurred in 55 patients (26.1%) and prolonged length of stay in 31 patients (14.7%)
  • Chole-Risk mod demonstrated the highest discrimination (AUC 0.925; OR 16.60; 95% CI 9.49–43.56)
  • For prolonged LOS, Chole-Risk mod had the best performance (AUC 0.869)

Cite This Study

Marcianò et al. (2026) studied this question.

synapsesocial.com/papers/6a002191c8f74e3340f9c6cdhttps://doi.org/10.3390/jcm15103595
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute Cholecystitis2013 · 461 citations
  2. 2Classification of Surgical Complications2004 · 31,681 citations
  3. 3Risk factors and mitigating measures associated with bile duct injury during cholecystectomy: meta-analysis2025 · 11 citations
  4. 4Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos)2017 · 1,548 citations