Key result
Heart transplantation establishes itself as standard advanced heart failure therapy through 50 years of multimodal advances.
Why the study?
This review explores the key milestones of the past 50 years of clinical heart transplantation for advanced heart failure and discusses current challenges and promising innovations on the clinical horizon.
This review summarizes 50 years of key milestones, current challenges, and future innovations in clinical heart transplantation for advanced heart failure.
Answers are grounded in this paper and cite their sources.
Supports heart transplantation as standard for advanced HF; leaves open optimization of preservation, immunosuppression, and surveillance.
Heart transplantation has become a standard therapy option for advanced heart failure. The translation of heart transplantation from innovative experiments to long-term clinical success has married prescient insights with discipline and organization in the domains of surgical techniques, organ preservation, immunosuppression, organ donation and transplantation logistics, infection control, and long-term graft surveillance. This review explores the key milestones of the past 50 years of heart transplantation and discusses current challenges and promising innovations on the clinical horizon.
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Stehlik et al. (2017) conducted a review in Advanced heart failure. Heart transplantation was evaluated. Heart transplantation has evolved over 50 years into a standard therapy option for advanced heart failure through advances in surgery, preservation, immunosuppression, and graft surveillance.
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