Plant-Derived Edible Nanoparticles and miRNAs: Emerging Frontier for Therapeutics and Targeted Drug-Delivery

Rigorous and timely studies have been conducted to develop natural and green nanomedicines wherein plant-derived edible nanoparticles (PDENs) have a great potential to be applied for targeted therapeutic delivery systems, because of their exclusive characteristics, namely desirable nanoparticle morphologies, environmentally safe and nonhazardous nature, appropriate tissue-specific targeting, and eminent potential for industrial pharmaceutical production. These nanoparticles can be exploited for drug transportation with distinctive benefits for treatment of diseases like cancers. In this Perspective, the properties and applications of PDENs are discussed with latest developments including the recent trends in plant-derived edible exosome-like nanoparticles and miRNAs.