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December 27, 2017TheranosticsOpen Access

Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development

Yun‐Chieh Sung Ya-Chi Liu Po‐Han Chao Chih-Chun Chang Pei-Ru Jin Ts-Ting Lin Ja-An Lin Hui‐Teng Cheng Jane Wang Charles Pin‐Kuang Lai Ling-Hsuan Chen Anthony Yan-Tang Wu Ting-Lun Ho Tsaiyu Chiang Dongyu Gao Dan G. Duda Yunching Chen

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Abstract

-induced murine model. Targeting HSCs represents a promising strategy to prevent the development and progression of fibrosis-associated HCC.

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Sung et al. (2017) studied this question.

synapsesocial.com/papers/6a006219b124fe581985dbd6 https://doi.org/10.7150/thno.21168

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