Why the study?
Does meloxicam 7.5 mg once daily improve gastrointestinal tolerability compared to piroxicam 20 mg once daily in patients with exacerbation of osteoarthritis?
Population
8,656 patients with exacerbation of osteoarthritis, international.
Comparison
Meloxicam 7.5 mg once daily for 28 days vs Piroxicam 20 mg once daily for 28 days
Design
RCT, Randomized, parallel-group, Double-blind, double-dummy
Follow-up
28 days
Authors
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Meloxicam improves GI tolerability versus piroxicam in osteoarthritis exacerbation; supports preferential NSAID selection in patients with GI risk.
Does meloxicam 7.5 mg once daily improve gastrointestinal tolerability compared to piroxicam 20 mg once daily in patients with exacerbation of osteoarthritis?
Meloxicam 7.5 mg once daily demonstrates improved gastrointestinal tolerability compared to piroxicam 20 mg once daily in patients with osteoarthritis exacerbation.
Dequeker et al. (1998) studied this question.
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