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April 6, 1991BMJOpen Access

By how much does dietary salt reduction lower blood pressure? II--Analysis of observational data within populations.

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Why the study?

Does dietary salt reduction lower blood pressure?

Population

Individuals from 14 published studies correlating blood pressure recordings against 24-hour sodium intake

Comparison

Dietary sodium intake vs Different levels of sodium intake

Design

Meta-analysis

Authors

CFChris FrostAstraZeneca (United Kingdom)MLM R LawPreventive CardiologyNWNicholas WaldPreventive Cardiology

Discussion

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Implication

Corrected within-population analyses support greater BP effects of sodium intake; confirms consistency with between-population comparisons.

Structured PICO

Does dietary salt reduction lower blood pressure?

P
Population
Individuals from 14 published studies correlating blood pressure recordings against 24-hour sodium intake
I
Intervention
Dietary sodium intake (measured by 24-hour sodium intake)
C
Comparator
Different levels of sodium intake
O
Outcome
Comparison of observed differences in blood pressure per 100 mmol/24 h difference in sodium intake with predicted differences calculated from between-population datasurrogate

Accounting for day-to-day variation in sodium intake reveals that within-population studies confirm the larger magnitude of association between blood pressure and sodium intake seen in between-population comparisons.

Cite This Study

Frost et al. (1991) studied this question.

synapsesocial.com/papers/6a00a637ef8139f8ff779f3ehttps://doi.org/10.1136/bmj.302.6780.815
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Also Consider

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  1. 1Factors of Risk in the Development of Coronary Heart Disease—Six-Year Follow-up Experience1961 · 1,834 citations
  2. 2Variability of Urinary Sodium and Potassium Excretion in North Chinese Men1987 · 18 citations
  3. 3Blood pressure and dietary salt in human populations1973 · 261 citations
  4. 4Characteristics of the association between salt intake and blood pressure in a sample of male working population in southern Italy1983 · 23 citations