Why the study?
Does ketorolac, alone and in combination with low-dose heparin, affect hemostasis in healthy male volunteers?
Population
12 healthy male volunteers
Comparison
Ketorolac active alone and in combination with… vs Ketorolac dummy/heparin dummy and ketorolac…
Design
Other, double-blind
Authors
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Warrants caution with ketorolac in patients at bleeding risk; confirms no heparin interaction on hemostasis.
Does ketorolac, alone and in combination with low-dose heparin, affect hemostasis in healthy male volunteers?
Ketorolac modestly prolongs bleeding time and inhibits platelet function without interacting with heparin, warranting caution in patients with underlying hemostatic disorders.
Ian A. Greer (1990) studied this question.
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