Why the study?
Does ketorolac affect hemostasis parameters compared to aspirin in volunteers?
Population
34 volunteers
Comparison
Ketorolac 30 mg intramuscularly four times a day… vs Intramuscular placebo and oral aspirin given on…
Design
RCT, randomized, double-blind
Follow-up
5 days
Authors
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Supports cautious ketorolac use in bleeding-prone patients; extends aspirin data by isolating bleeding-time effects in RCT volunteers.
Does ketorolac affect hemostasis parameters compared to aspirin in volunteers?
Ketorolac modestly prolongs bleeding time compared to aspirin but does not significantly affect other routine coagulation parameters in volunteers.
Conrad et al. (1988) studied this question.