Population
Human platelets, stably expressed placental or endothelial isoforms of the thromboxane receptor, healthy…
Design
Preclinical
Authors
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Systemic 8-epi-PGF2alpha concentrations are unlikely to modulate platelets in vivo; leaves open a distinct receptor mechanism for further study.
8-epi-PGF2alpha amplifies platelet activation via a distinct receptor rather than thromboxane receptors, though typical systemic concentrations are insufficient to cause this effect in vivo.
Praticò et al. (1996) studied this question.
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