Why the study?
Do pacing-induced changes in cycle length affect the refractory periods of the atrium, A-V node, and His-Purkinje system in patients?
Population
24 patients
Comparison
Pacing-induced changes in cycle length using the… vs Different cycle lengths within the same patient
Authors
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May inform cycle-length selection in EP studies; leaves open translation to arrhythmia management.
Do pacing-induced changes in cycle length affect the refractory periods of the atrium, A-V node, and His-Purkinje system in patients?
In humans, decreasing cycle length shortens atrial and His-Purkinje refractory periods but lengthens A-V nodal effective refractory periods, providing insight into aberrant conduction.
Denes et al. (1974) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: