Key result
Sedentary behavior links to stroke in older adults, while physical activity is inversely associated.
Cross-Sectional (n=3,010)
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Objective: The aim of this study was to investigate the relationship between physical activity, sedentary behavior and stroke in people aged 60 years and older. Methods: The study included 3,010 participants aged 60 and older from the National Health and Nutrition Examination Survey (NHANES). Data on sedentary behavior, physical activity and stroke were obtained through questionnaires. Statistical analyses were performed using a complex multistage sampling design and weighted multivariate logistic regression. Smoothed curve fitting and threshold effects analyses were used to explore non-linear relationships between physical activity, sedentary behavior and stroke. C-reactive protein mediated the association between sedentary behavior and stroke among older adults, with a mediation of 3.64%. Conclusion: In people aged 60 years and older, sedentary behavior was positively associated with stroke, whereas physical activity was negatively associated with stroke, and C-reactive protein mediated the relationship between sedentary behavior and stroke.
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Bai et al. (2024) conducted a cross-sectional in stroke (n=3,010). Physical activity and sedentary behavior was evaluated on stroke (p=0.003). Sedentary behavior was positively associated with stroke in adults ≥60, while physical activity was negatively associated (C-reactive protein mediation 3.64%).
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