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July 24, 2014Journal of VirologyOpen Access

Virus-Specific Memory CD8 T Cells Provide Substantial Protection from Lethal Severe Acute Respiratory Syndrome Coronavirus Infection

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Authors

RCRudragouda ChannappanavarOklahoma State UniversityCFCraig FettUniversity of North Carolina at Chapel HillJZJincun ZhaoShanghaiTech University

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Channappanavar et al. (2014) studied this question.

synapsesocial.com/papers/6a01311db124fe58198644a2https://doi.org/10.1128/jvi.01505-14
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cutting Edge: Rapid In Vivo Killing by Memory CD8 T Cells2003 · 450 citations
  2. 2Immunity to Respiratory Viruses2008 · 259 citations
  3. 3Lung-resident memory CD8 T cells (TRM) are indispensable for optimal cross-protection against pulmonary virus infection2013 · 561 citations
  4. 4Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection2011 · 661 citations
  5. 5Cellular Immune Responses to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection in Senescent BALB/c Mice: CD4<sup>+</sup>T Cells Are Important in Control of SARS-CoV Infection2009 · 420 citations