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August 6, 2015Journal of Biological ChemistryOpen Access

Itch WW Domains Inhibit Its E3 Ubiquitin Ligase Activity by Blocking E2-E3 Ligase Trans-thiolation

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Authors

CRChristopher RilingSpark Therapeutics (United States)HKHari KamaduraiIntarcia Therapeutics (United States)SKSuresh KumarManagement and Science University

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Riling et al. (2015) studied this question.

synapsesocial.com/papers/6a013e072ff633f365784e2dhttps://doi.org/10.1074/jbc.m115.649269
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1UniProt: a hub for protein information2014 · 5,359 citations
  2. 2Structure of an E6AP-UbcH7 Complex: Insights into Ubiquitination by the E2-E3 Enzyme Cascade1999 · 575 citations