Why the study?
Does gemfibrozil improve insulin sensitivity to fat metabolism in subjects with type 2 diabetes and hypertriglyceridaemia?
Does gemfibrozil improve insulin sensitivity to fat metabolism in subjects with type 2 diabetes and hypertriglyceridaemia?
Gemfibrozil effectively lowers triglycerides, NEFA, and ketones in type 2 diabetes patients but does not improve insulin sensitivity to glucose or fat metabolism.
No takes yet. Share an insight, caveat, or question.
Gemfibrozil lowers triglycerides and NEFA without improving insulin sensitivity; challenges expectations of metabolic benefits beyond lipids in type 2 diabetes.
Whitelaw et al. (2002) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: