Why the study?
Hypertension and arterial stiffening in CKD are related to extracellular fluid volume expansion, prompting the hypothesis that CKD patients with uncontrolled hypertension are more likely to have fluid volume expansion and increased arterial stiffness.
Is uncontrolled hypertension in patients with CKD associated with extracellular fluid volume expansion and increased arterial stiffness?
Population
82 adult hypertensive patients with mild-severe CKD
Comparison
Uncontrolled hypertension vs normotensive or blood pressure at target
Design
Cross-sectional study
Authors
Loading...
Fluid expansion links to uncontrolled hypertension and stiffness in CKD; hypothesis-generating, requiring prospective trials before practice change.
Is uncontrolled hypertension in patients with CKD associated with extracellular fluid volume expansion and increased arterial stiffness?
In patients with CKD, uncontrolled hypertension is independently associated with extracellular fluid volume expansion and increased arterial stiffness.
Braam et al. (2019) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: