Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies
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Implication
Review reveals diverse biological activities and clinical potential of fucoidan, highlighting its value for human disease treatment and functional product development.
Key Points
- To synthesize recent scientific progress regarding the biological activities of fucoidan and evaluate how its molecular structure mediates therapeutic effects in human disease.
- Literature review of recent pre-clinical and clinical studies evaluating fucoidan derived from marine sources.
- Analysis of structural characteristics, primarily L-fucose and sulphate group content, in relation to biological functionality.
- Fucoidan exhibits classical bioactivities including antitumor, antioxidant, anticoagulant, antithrombotic, immunoregulatory, antiviral, and anti-inflammatory actions directly tied to its unique structural composition.
- Recent evidence demonstrates broader therapeutic benefits, notably in alleviating metabolic syndrome, preserving gastrointestinal integrity, facilitating bone health, and modulating angiogenesis.
Cite This Study
Wang et al. (2019) studied this question.