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May 11, 2026Analytical Chemistry1 citations

Pathology-Responsive Nanoprobes for NIR-II Imaging of Acute Kidney Injury

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WSWuyue SuWBWenjing BaiSSShuangyan Song

Key Points

  • The aim is to explore the use of pathology-responsive nanoprobes for noninvasive NIR-II imaging in diagnosing acute kidney injury (AKI).
  • Utilization of -acetylcysteine (NAC) therapy to enhance renal recovery and reduce apoptosis.
  • Assessment of signal-to-noise ratio for effective imaging in AKI cases.
  • Evaluation of therapeutic effectiveness through imaging feedback.
  • Demonstrated significant improvement in early AKI diagnosis and severity assessment with nanoprobes.
  • NAC therapy showed enhanced penetration of imaging agents leading to better renal visualization.
  • Findings indicate a strong correlation between imaging results and renal recovery outcomes.

Abstract

-acetylcysteine (NAC) therapy, aligning with renal recovery and reducing apoptosis with enhanced penetration and signal-to-noise ratio, offering a noninvasive platform for early AKI diagnosis, severity assessment, and therapeutic evaluation.

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Cite This Study

Su et al. (2026) studied this question.

synapsesocial.com/papers/6a0171ce3a9f334c28271d42https://doi.org/10.1021/acs.analchem.6c00589
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