Key result
Cognitive behavioral therapy reduces depressive symptoms and improves quality of life in HF patients vs. controls.
Why the study?
The study aimed to provide an up-to-date umbrella review of existing meta-analyses evaluating cognitive behavioral therapy in patients with heart failure.
Does cognitive behavioral therapy improve psychological and physical outcomes compared with control conditions in patients with heart failure?
Systematic Review (n=1,687)
Does cognitive behavioral therapy improve psychological and physical outcomes compared with control conditions in patients with heart failure?
Cognitive behavioral therapy provides significant psychological and physical benefits for patients with heart failure, though effects vary by follow-up timepoint and specific outcome measures.
Answers are grounded in this paper and cite their sources.
Supports CBT for depressed HF patients; confirms efficacy from umbrella review of five meta-analyses of 18 RCTs.[[1]](https://www.springermedizin.de/face-to-face-and-internet-based-cognitive-behavioral-therapy-for/52395994)[[2]](https://pubmed.ncbi.nlm.nih.
Purpose of review The present study aims to provide an up-to-date umbrella review of existing meta-analyses of randomized control trials (RCT) of cognitive behavioral therapy (CBT) among patients with heart failure (HF). Recent findings The umbrella review covered five meta-analyses published in the past five years with 18 primary studies (conducted between 2010 and 2022) of 1,687 non-duplicated patients aged 51.63 to 77.40. Primary studies originated from the USA, Sweden, Netherlands, China, Iran, and Philippines. Common benefits of CBT included depressive symptoms (89%), quality of life (56%), anxiety symptoms (39%), self-care (33%), 6-minute walk distance (33%), and health status (17%). Evidence varied depending on the timepoint of follow-up assessment and the specific measurement used to evaluate the outcome. No meta-analyses pooled the effect sizes for iCBT and analyzed the specific therapeutic elements in CBT. No meta-regression was performed. Summary Individual participant data meta-analyses with meta-regression should be performed to identify common moderators and factors that can influence treatment adherence. The current research would also benefit from additional RCT evidence focusing specifically on iCBT for patients with HF.
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Liu et al. (2026) conducted a systematic review in Heart Failure (n=1,687). Cognitive Behavioral Therapy (CBT) vs. Usual care, waitlist controls, active controls was evaluated on Depressive symptoms (1 week to 12 months follow-up) (SMD -0.68, 95% CI -0.87 to -0.49). Cognitive behavioral therapy significantly reduced depressive symptoms and improved quality of life in patients with heart failure compared to control conditions.
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