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May 8, 2026Clinical and Experimental Dermatology

Reconsidering tumour boundaries: implications of peritumoral Wnt dysregulation in penile squamous cell carcinoma

Patrick Steven Tajanlangit Sean Michael Tajanlangit

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Key Points

The aim is to explore how peritumoral Wnt dysregulation affects tumour boundaries in penile squamous cell carcinoma.
Review of insights from Wnt-related protein expression
Evaluation of field effects in carcinoma at the peritumoral zone
Highlighting the role of Wnt dysregulation in altering tumour margins
Suggesting potential biomarkers for clinical assessment in squamous cell carcinoma

Implication

Response addresses Wnt dysregulation impacts on tumour boundaries in penile squamous cell carcinoma, suggesting significant clinical implications.

Abstract

Response to ‘Field effects in penile squamous cell carcinoma: insights from Wnt-related protein expression’ by Kravvas et al

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Cite This Study

Tajanlangit et al. (2026) studied this question.

synapsesocial.com/papers/6a0172813a9f334c28272b44 https://doi.org/10.1093/ced/llag201

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Field effects in penile squamous cell carcinoma: Insights from Wnt-related protein expressionReview · 2026 · 1 citations
2The role of the tumor microenvironment in penile carcinoma and emerging therapeutic concepts: A reviewHuman Clinical Trial · 2026 · 1 citations
3Interplay of PD-L1, FOXP3, and CD8 in the Immune Microenvironment of Penile Squamous Cell Carcinoma: Expression Profiles and Correlations2025 · 1 citations
4Surgical Margin Status and Minimal Margin Width in Penile Squamous Cell Carcinoma: Local Recurrence and Survival Outcomes in a Single-Centre CohortCohort Study · 2026 · 1 citations
5MP61-09 POTENTIAL SURVIVAL BENEFITS OF LYMPH NODE DISSECTION IN LYMPH NODE NEGATIVE PENILE SQUAMOUS CELL CARCINOMA PATIENTS: A FOCUS ON T2+N0M0 STAGE2024

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MP61-03 PROGRAMMED DEATH-LIGAND (PD-L1) EXPRESSION AND LYMPH NODE INVOLVEMENT IN PENILE SQUAMOUS CELL CARCINOMA2024
Spatial and molecular determinants of response in penile squamous cell carcinoma.2026

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