Population
Poliovirus type 1 (PV-1) and its RNA in FRhK-4 host cells
Comparison
Inactivation by UV, hypochlorite, and heat vs Virion infectivity vs RNA infectivity
Design
Preclinical
Authors
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Informs mechanistic understanding of viral inactivation; leaves open translation to clinical disinfection strategies pending further studies.
Viral RNA is a primary target of UV and hypochlorite inactivations, whereas the sole target of thermal inactivation is the viral capsid.
Nuanualsuwan et al. (2003) studied this question.
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