Why the study?
Does maternal cardiac output measured in the first trimester predict the development of preeclampsia, PIH, or SGA?
Population
4,293 pregnant women attending routine care between 11 and 13 weeks of gestation.
Comparison
Measurement of maternal cardiac output by… vs Unaffected pregnancies (n=3,591).
Design
Cohort
Authors
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First-trimester cardiac output may aid preeclampsia risk stratification; hypothesis-generating for screening models pending prospective validation.
Does maternal cardiac output measured in the first trimester predict the development of preeclampsia, PIH, or SGA?
Alterations in maternal cardiac output measured by echocardiography in the first trimester predate the clinical onset of preeclampsia, PIH, and SGA, offering potential predictive value.
Paco et al. (2008) studied this question.
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