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March 9, 1995New England Journal of MedicineOpen Access

Hemostatic Factors and the Risk of Myocardial Infarction or Sudden Death in Patients with Angina Pectoris

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Why the study?

Are elevated baseline concentrations of hemostatic factors associated with an increased risk of myocardial infarction or sudden death in patients with angina pectoris?

Population

3,043 patients with angina pectoris who underwent coronary angiography

Design

Cohort

Follow-up

two years

Authors

STSimon G. ThompsonPreventive CardiologyJKJoachim KienastUniversity of MünsterSPStephen PykePfizer (United Kingdom)

Discussion

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Implication

May aid risk stratification in angina pectoris; leaves open whether modulating these factors improves outcomes.

Structured PICO

Are elevated baseline concentrations of hemostatic factors associated with an increased risk of myocardial infarction or sudden death in patients with angina pectoris?

P
Population
3,043 patients with angina pectoris who underwent coronary angiography
O
Outcome
Incidence of myocardial infarction or sudden coronary deathhard clinical

In patients with angina pectoris, elevated baseline levels of fibrinogen, von Willebrand factor, and t-PA antigen are independent predictors of subsequent myocardial infarction or sudden death.

Cite This Study

Thompson et al. (1995) studied this question.

synapsesocial.com/papers/6a01b8cef58f6e6cfdd8bb5fhttps://doi.org/10.1056/nejm199503093321003
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