Population
Voltage-activated potassium channel protein (Kv)
Design
Preclinical
Authors
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Supports refined Kv channel models in research; leaves open human cardiac translation.
A novel strategy using high-order double-mutant cycle-coupling analysis provides direct evidence for a concerted all-or-none activation gate opening in the Kv channel pore domain.
Zandany et al. (2008) studied this question.
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