July 1, 2009Current Protocols in Neuroscience
Simple Behavioral Assessment of Mouse Olfaction
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Implication
Methodological protocol demonstrates behavioral assays of olfaction in mice, facilitating standardized screening for anosmia and odor discrimination.
Key Points
- To establish rapid, accessible behavioral testing protocols for detecting anosmia and assessing odor discrimination capabilities in mice.
- Application of the buried food test to determine the ability of mice to locate volatile food odors beneath bedding.
- Implementation of the olfactory habituation/dishabituation assay to test discrimination between social and nonsocial odors.
- Integration of a non-contact odor presentation protocol and a standardized mouse urine collection procedure.
- Provides reliable qualitative differentiation between normal olfactory function and anosmia across experimental mouse cohorts.
- Establishes a standardized framework for evaluating both social and nonsocial scent differentiation using basic laboratory equipment.
Cite This Study
Yang et al. (2009) studied this question.