The interstitial cell of the green hydra is formed by dedifferentiation of specialized gastrodermal cells. Similarly, the epidermal epitheliomuscular cells are probably formed by direct difjerentiation of algae-laden digestive cells that lose their algae and enclosed food droplets, migrate to the periphery of the animal, and begin the mucous secretion characteristic of epidermal cells.
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Haynes et al. (1963) studied this question.
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