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February 4, 2020Critical CareOpen Access

Vasoplegic syndrome following cardiothoracic surgery—review of pathophysiology and update of treatment options

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Why the study?

Vasoplegic syndrome commonly follows cardiothoracic surgery, but research into its treatment is limited and mostly extrapolated from septic shock.

Design

Review

Authors

LBLaurence W. BusseNBNicholas BarkerCPChristopher Petersen

Discussion

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Overview

Treatment of post-cardiac surgery vasoplegia warrants caution given limited evidence; leaves open dedicated trials of novel catecholamine-sparing options.

Structured PICO

P
Population
Patients with vasoplegic syndrome following cardiothoracic surgery
I
Intervention
Treatment options including catecholamine-sparing agents and novel treatments

This review highlights the complex pathophysiology of vasoplegic syndrome post-cardiothoracic surgery and the evolving, albeit limited, treatment options including catecholamine-sparing agents.

Limitations

  • Research into treatment of this syndrome is limited
  • Large clinical trials are needed to confirm potential benefits of novel treatment options

Cite This Study

Busse et al. (2020) studied this question.

synapsesocial.com/papers/6a01f8656668471b61d8b147https://doi.org/10.1186/s13054-020-2743-8
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